TGFB3

Across TCGA cell cohorts, TGFB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,230 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TGFB3-associated GO terms across cancer lineages are Vacuole organization, Aerobic respiration, and Negative regulation of myoblast fusion. Each is linked with TGFB3 in more than 11 cancer types. Because this analysis shows association rather than direction, both TGFB3-to-partner and partner-to-TGFB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by TGFB3-low versus TGFB3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFB3→partner) and Y-score (partner→TGFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Vacuole organization →	+0.047	+1.024	.006	.007	3	11
UPPER_AERODIGESTIVE_TRACT	Aerobic respiration →	+0.104	+1.231	<.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.141	+1.580	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.140	+1.533	<.001	<.001	3	11
PANCREAS	Negative regulation of chromosome condensation →	+0.155	+0.760	<.001	.004	2	12
PANCREAS	DNA-templated transcription initiation →	+0.050	+1.002	.001	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,230 associations by consensus.

Vacuole organization by TGFB3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →