TGFB1I1

Across TCGA cell cohorts, TGFB1I1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,601 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TGFB1I1-associated GO terms across cancer lineages are Positive regulation of supramolecular fiber organization, Positive regulation of cytoskeleton organization, and Regulation of coagulation. Each is linked with TGFB1I1 in more than 14 cancer types. Because this analysis shows association rather than direction, both TGFB1I1-to-partner and partner-to-TGFB1I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of supramolecular fiber organization grouped by TGFB1I1-low versus TGFB1I1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFB1I1→partner) and Y-score (partner→TGFB1I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of supramolecular fiber organization →	+0.103	+3.686	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Positive regulation of cytoskeleton organization →	+0.085	+2.334	.003	.002	3	15
LUNG_NSCLC_LUSC	Regulation of coagulation →	+0.217	+3.200	.001	<.001	3	14
BREAST	Endodermal cell differentiation →	+0.180	+2.676	<.001	<.001	3	14
BONE	Integrin-mediated signaling pathway →	+0.271	+4.087	<.001	<.001	3	13
BONE	Blood coagulation →	+0.134	+3.498	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,601 associations by consensus.

Positive regulation of supramolecular fiber organization by TGFB1I1 expression — LIVER

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