TGFB1

Across TCGA patient cohorts, TGFB1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TGFB1-associated genes across cancer lineages are CD8+ naive T-cells. Each is linked with TGFB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TGFB1-to-partner and partner-to-TGFB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by TGFB1-low versus TGFB1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFB1→partner) and Y-score (partner→TGFB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.043	+2.212	.002	.034	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD8+ naive T-cells by TGFB1 expression — UCEC

Explore this box plot interactively →