TGFA

Across TCGA patient cohorts, TGFA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,336 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TGFA-associated proteins across cancer lineages are AHNAK2_S5707, OSBPL3, and LAMB3. Each is linked with TGFA in more than 5 cancer types. Because this analysis shows association rather than direction, both TGFA-to-partner and partner-to-TGFA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFA versus AHNAK2_S5707 in LUAD, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFA→partner) and Y-score (partner→TGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	AHNAK2_S5707 →	+1.643	+0.862	<.001	.009	3	6
OV	OSBPL3 →	+0.476	+1.286	.002	.001	3	5
OV	LAMB3 →	+0.862	+1.257	<.001	<.001	3	5
HNSC	RTKN →	+0.525	+0.966	<.001	<.001	3	5
LSCC	S100A2 →	+1.744	+1.057	.001	<.001	3	5
BRCA	SCEL_S68 →	+2.598	+1.375	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,336 associations by consensus.

TGFA vs AHNAK2_S5707 — LUAD

Explore this scatter interactively →