TGFA

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TGFA mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TGFA-associated genes across cancer lineages are Adipocytes. Each is linked with TGFA in more than 1 cancer types. Because this analysis shows association rather than direction, both TGFA-to-partner and partner-to-TGFA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by TGFA-low versus TGFA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFA→partner) and Y-score (partner→TGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAdipocytes →+0.023+2.729.017.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Adipocytes by TGFA expression — UCEC

Box plot of Adipocytes in TGFA-low vs TGFA-high samples in UCEC.

Explore this box plot interactively →

Exploration