TGFA

Across TCGA cell cohorts, TGFA mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TGFA-associated genes across cancer lineages are OPN4. Each is linked with TGFA in more than 1 cancer types. Because this analysis shows association rather than direction, both TGFA-to-partner and partner-to-TGFA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN4 grouped by TGFA-low versus TGFA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFA→partner) and Y-score (partner→TGFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OPN4 →	+0.013	+4.930	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OPN4 by TGFA expression — LARGE_INTESTINE

Explore this box plot interactively →