TFG

Across TCGA pan-cancer cohorts, TFG mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TFG data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher TFG mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TFG expression acts as an unfavorable survival marker.

GBM, LUAD, and LSCC are the cancer types where TFG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.648	0.907	.014	9	view →
LUAD	DFS	Median	III,IV	0.432	0.925	.047	3	view →
LSCC	OS	Median	All	0.800	1.000	.044	1	view →
HNSC	DFS	Median	IV	0.924	1.000	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TFG–GBM (OS)

Open the GBM breakdown →