TFG

Across TCGA cell cohorts, TFG RNA expression is significantly associated with the go_rna of many other GO terms, with 3,537 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TFG-associated GO terms across cancer lineages are Postsynapse to nucleus signaling pathway, Regulation of early endosome to late endosome transport, and Positive regulation of viral process. Each is linked with TFG in more than 13 cancer types. Because this analysis shows association rather than direction, both TFG-to-partner and partner-to-TFG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Postsynapse to nucleus signaling pathway grouped by TFG-low versus TFG-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFG→partner) and Y-score (partner→TFG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Postsynapse to nucleus signaling pathway →	+0.137	+0.769	<.001	.001	3	14
BREAST	Regulation of early endosome to late endosome transport →	+0.112	+0.543	<.001	.001	3	11
BLOOD_Lymphoma	Positive regulation of viral process →	+0.087	+1.247	<.001	<.001	3	10
BLOOD_Myeloma	Regulation of protein binding →	+0.098	+0.634	<.001	<.001	3	10
BLOOD_Lymphoma	Myoblast migration involved in skeletal muscle regeneration →	+0.178	+0.841	<.001	<.001	3	10
BLOOD_Lymphoma	Golgi vesicle transport →	+0.072	+1.283	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,537 associations by consensus.

Postsynapse to nucleus signaling pathway by TFG expression — BREAST

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