TFF2

Across TCGA cell cohorts, TFF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,397 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible TFF2-associated GO terms across cancer lineages are Intracellular sodium ion homeostasis, Cellular response to fatty acid, and Positive regulation of potassium ion import across plasma membrane. Each is linked with TFF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TFF2-to-partner and partner-to-TFF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular sodium ion homeostasis grouped by TFF2-low versus TFF2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFF2→partner) and Y-score (partner→TFF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Intracellular sodium ion homeostasis →	+0.254	+3.044	.001	.004	3	6
URINARY_TRACT	Cellular response to fatty acid →	+0.165	+1.092	<.001	.004	3	5
PANCREAS	Positive regulation of potassium ion import across plasma membrane →	+0.218	+4.432	<.001	<.001	3	5
PANCREAS	Circadian regulation of gene expression →	+0.054	+3.176	.001	.002	3	5
PANCREAS	Medium-chain fatty acid catabolic process →	+0.165	+3.711	.005	.005	3	5
URINARY_TRACT	Positive regulation of proteolysis →	+0.075	+1.194	<.001	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,397 associations by consensus.

Intracellular sodium ion homeostasis by TFF2 expression — STOMACH

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