TFF1

Across TCGA cell cohorts, TFF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,700 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TFF1-associated GO terms across cancer lineages are Aorta smooth muscle tissue morphogenesis, Cytotoxic T cell degranulation, and Acetylcholine biosynthetic process. Each is linked with TFF1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TFF1-to-partner and partner-to-TFF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aorta smooth muscle tissue morphogenesis grouped by TFF1-low versus TFF1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFF1→partner) and Y-score (partner→TFF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Aorta smooth muscle tissue morphogenesis →	-0.921	-4.892	<.001	<.001	3	8
BREAST	Cytotoxic T cell degranulation →	+0.209	+4.572	.004	<.001	3	7
STOMACH	Acetylcholine biosynthetic process →	+1.392	+3.180	<.001	<.001	3	7
BLOOD_Lymphoma	2-oxoglutarate metabolic process →	+0.071	+0.347	<.001	.001	3	7
URINARY_TRACT	Regulation of clathrin coat assembly →	+0.239	+1.749	<.001	<.001	3	7
STOMACH	'de novo' GDP-L-fucose biosynthetic process →	+0.199	+4.904	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,700 associations by consensus.

Aorta smooth muscle tissue morphogenesis by TFF1 expression — BREAST

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