TFDP2

Across TCGA patient cohorts, TFDP2 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TFDP2-associated genes across cancer lineages are ASNS, EGFR_pY1068, and EGFR. Each is linked with TFDP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TFDP2-to-partner and partner-to-TFDP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by TFDP2-low versus TFDP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFDP2→partner) and Y-score (partner→TFDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.722	+3.807	<.001	<.001	3	2
UCEC	EGFR_pY1068 →	-0.225	-3.584	.019	.002	3	1
UCEC	EGFR →	-0.176	-2.433	.004	.018	3	1
UCEC	eIF4E →	+0.238	+3.807	.003	<.001	3	1
UCEC	eIF4G →	+0.282	+2.087	.017	.005	3	1
UCEC	A-Raf_pS299 →	-0.098	-2.000	.032	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ASNS by TFDP2 expression — UCEC

Explore this box plot interactively →