TFDP2

Across TCGA cell cohorts, TFDP2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TFDP2-associated genes across cancer lineages are NPHS2, PRDM7, and TKTL2. Each is linked with TFDP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TFDP2-to-partner and partner-to-TFDP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPHS2 grouped by TFDP2-low versus TFDP2-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFDP2→partner) and Y-score (partner→TFDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	NPHS2 →	+0.013	+4.736	<.001	.009	3	1
LARGE_INTESTINE	PRDM7 →	+0.255	+3.302	<.001	.006	3	1
LARGE_INTESTINE	TKTL2 →	+0.040	+3.187	<.001	.006	3	1
LARGE_INTESTINE	GFRA2 →	+0.030	+3.839	.008	.001	3	1
LARGE_INTESTINE	OR4F4 →	+0.021	+3.425	<.001	<.001	3	1
STOMACH	CT47A6 →	+0.046	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

NPHS2 by TFDP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →