Across TCGA pan-cancer cohorts, TFDP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TFDP1 data layer compared with 28 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TFDP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TFDP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where TFDP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.911	0.579	.001	43	view →
LUAD	DFS	Tertile	III,IV	0.916	0.526	.006	23	view →
UCEC	OS	Median	All	1.000	0.905	.009	10	view →
HNSC	DFS	Tertile	II,III,IV	0.798	0.546	.018	8	view →
PDAC	DFS	Tertile	All	0.552	0.285	.026	8	view →
OV	DFS	Median	All	0.866	1.000	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: TFDP1 tumor-vs-normal RNA expression · all TFDP1 data types