Across TCGA patient cohorts, TFDP1 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TFDP1-associated genes across cancer lineages are Di-Ras3, MSH6, and NF2. Each is linked with TFDP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TFDP1-to-partner and partner-to-TFDP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFDP1→partner) and Y-score (partner→TFDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Di-Ras3 →	-0.170	-2.649	<.001	<.001	3	3
UCEC	MSH6 →	-0.244	-1.584	.011	.032	3	2
UCEC	NF2 →	+0.171	+1.280	.006	.049	3	2
UCEC	Caspase-7-cleavedD198 →	+0.665	+2.341	<.001	<.001	3	2
UCEC	C-Raf →	+0.140	+1.584	<.001	.008	3	2
UCEC	14-3-3_beta →	-0.100	-2.388	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

TFDP1 survival (RNA) · tumor vs normal (RNA) · all TFDP1 data types