TFCP2L1

Across TCGA cell cohorts, TFCP2L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,022 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TFCP2L1-associated GO terms across cancer lineages are Septin cytoskeleton organization, Regulation of white fat cell proliferation, and Positive regulation of collagen metabolic process. Each is linked with TFCP2L1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TFCP2L1-to-partner and partner-to-TFCP2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Septin cytoskeleton organization grouped by TFCP2L1-low versus TFCP2L1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFCP2L1→partner) and Y-score (partner→TFCP2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Septin cytoskeleton organization →	+0.148	+1.412	.005	<.001	3	8
LIVER	Regulation of white fat cell proliferation →	-0.174	-0.478	.005	.007	3	7
STOMACH	Positive regulation of collagen metabolic process →	-0.093	-1.217	.001	.002	3	7
BREAST	Positive regulation of telomerase RNA localization to Cajal body →	+0.077	+1.603	.001	.001	3	7
BREAST	Negative regulation of myoblast fusion →	+0.079	+1.388	<.001	.001	3	6
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.115	+1.719	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,022 associations by consensus.

Septin cytoskeleton organization by TFCP2L1 expression — STOMACH

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