TFCP2

Across TCGA cell cohorts, TFCP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,465 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TFCP2-associated GO terms across cancer lineages are Negative regulation of transcription by RNA polymerase III, Nuclear transport, and Retrograde transport, endosome to Golgi. Each is linked with TFCP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TFCP2-to-partner and partner-to-TFCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription by RNA polymerase III grouped by TFCP2-low versus TFCP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFCP2→partner) and Y-score (partner→TFCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription by RNA polymerase III →	+0.126	+0.944	<.001	.004	3	12
BREAST	Nuclear transport →	+0.053	+1.262	.001	.007	3	10
CNS	Retrograde transport, endosome to Golgi →	+0.043	+0.607	.001	.008	3	9
BONE	RNA catabolic process →	+0.082	+0.788	<.001	.001	3	9
BREAST	Nucleocytoplasmic transport →	+0.053	+1.262	.001	.007	3	9
LARGE_INTESTINE	Heterochromatin formation →	+0.061	+0.703	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,465 associations by consensus.

Negative regulation of transcription by RNA polymerase III by TFCP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →