TFCP2

Across TCGA cell cohorts, TFCP2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TFCP2-associated genes across cancer lineages are IFNA14, C5orf52, and CEACAM3. Each is linked with TFCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TFCP2-to-partner and partner-to-TFCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA14 grouped by TFCP2-low versus TFCP2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFCP2→partner) and Y-score (partner→TFCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFNA14 →	+0.032	+5.369	<.001	.004	3	1
BLOOD_Leukemia	C5orf52 →	+0.022	+4.984	<.001	.002	3	1
LARGE_INTESTINE	CEACAM3 →	+0.553	+3.517	<.001	.003	3	1
LARGE_INTESTINE	SNTG2 →	+0.111	+3.052	.008	.003	3	1
LARGE_INTESTINE	NEXMIF →	+0.212	+2.933	<.001	.003	3	1
BLOOD_Lymphoma	MRGPRE →	+0.022	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

IFNA14 by TFCP2 expression — SOFT_TISSUE

Explore this box plot interactively →