TFAP4

Across TCGA patient cohorts, TFAP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,874 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TFAP4-associated proteins across cancer lineages are SMC3, TFAP4_S124, and WRNIP1. Each is linked with TFAP4 in more than 8 cancer types. Because this analysis shows association rather than direction, both TFAP4-to-partner and partner-to-TFAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFAP4 versus SMC3 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP4→partner) and Y-score (partner→TFAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC3 →	+0.303	+0.409	<.001	<.001	3	9
BRCA	TFAP4_S124 →	+0.828	+0.651	<.001	<.001	3	8
LSCC	WRNIP1 →	+0.375	+0.508	<.001	<.001	3	7
GBM	TCERG1 →	+0.222	+0.314	<.001	<.001	3	7
BRCA	POLR2E →	+0.245	+0.712	<.001	<.001	3	7
LSCC	NUP93 →	+0.227	+0.629	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,874 associations by consensus.

TFAP4 vs SMC3 — GBM

Explore this scatter interactively →