TFAP4

Across TCGA patient cohorts, TFAP4 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,532 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TFAP4-associated proteins across cancer lineages are TFAP4_S124, SMC1A, and TPR. Each is linked with TFAP4 in more than 7 cancer types. Because this analysis shows association rather than direction, both TFAP4-to-partner and partner-to-TFAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFAP4 versus TFAP4_S124 in BRCA, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP4→partner) and Y-score (partner→TFAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TFAP4_S124 →	+0.978	+0.417	<.001	<.001	3	8
LSCC	SMC1A →	+0.304	+0.542	<.001	<.001	3	8
LSCC	TPR →	+0.205	+0.395	<.001	<.001	3	7
LSCC	WRNIP1 →	+0.357	+0.350	<.001	<.001	3	7
LSCC	RSRC2 →	+0.214	+0.366	<.001	<.001	3	7
HNSC	SFPQ →	+0.201	+0.375	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,532 associations by consensus.

TFAP4 vs TFAP4_S124 — BRCA

Explore this scatter interactively →