TFAP2E

Across TCGA patient cohorts, TFAP2E protein abundance is significantly associated with the RNA expression of many other genes, with 3,873 significant associations in total. OV shows the largest number of these associations.

The most reproducible TFAP2E-associated genes across cancer lineages are IGHV4-59, CXCL12, and KCNJ8. Each is linked with TFAP2E in more than 4 cancer types. Because this analysis shows association rather than direction, both TFAP2E-to-partner and partner-to-TFAP2E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFAP2E versus IGHV4-59 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP2E→partner) and Y-score (partner→TFAP2E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGHV4-59 →	+3.541	+0.989	<.001	<.001	3	5
OV	CXCL12 →	+1.425	+0.863	.004	.003	3	4
OV	KCNJ8 →	+0.777	+0.729	.008	.005	3	4
OV	CDO1 →	+1.671	+0.929	<.001	<.001	3	4
OV	SFRP2 →	+2.759	+0.794	.004	.005	3	4
BRCA	KCNE4 →	+1.679	+0.561	.007	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,873 associations by consensus.

TFAP2E vs IGHV4-59 — OV

Explore this scatter interactively →