TFAP2C

Across TCGA patient cohorts, TFAP2C protein abundance is significantly associated with the RNA expression of many other genes, with 11,071 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TFAP2C-associated genes across cancer lineages are CDC20, CENPF, and KIF14. Each is linked with TFAP2C in more than 3 cancer types. Because this analysis shows association rather than direction, both TFAP2C-to-partner and partner-to-TFAP2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFAP2C versus CDC20 in UCEC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP2C→partner) and Y-score (partner→TFAP2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDC20 →	+1.400	+0.357	.004	.002	3	4
BRCA	CENPF →	+1.167	+0.530	<.001	.001	3	4
BRCA	KIF14 →	+1.273	+0.624	<.001	<.001	3	4
BRCA	TP53BP2 →	+0.851	+0.382	<.001	.007	3	4
UCEC	RAE1 →	+0.666	+0.495	.002	.001	2	4
HNSC	TPD52L2 →	+0.622	+0.520	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,071 associations by consensus.

TFAP2C vs CDC20 — UCEC

Explore this scatter interactively →