TFAP2C

Across TCGA cell cohorts, TFAP2C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,078 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TFAP2C-associated GO terms across cancer lineages are Morula formation, Inner cell mass cell differentiation, and Positive regulation of proteolysis. Each is linked with TFAP2C in more than 14 cancer types. Because this analysis shows association rather than direction, both TFAP2C-to-partner and partner-to-TFAP2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Morula formation grouped by TFAP2C-low versus TFAP2C-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP2C→partner) and Y-score (partner→TFAP2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Morula formation →	+1.851	+2.784	<.001	<.001	3	15
STOMACH	Inner cell mass cell differentiation →	+1.561	+3.194	<.001	<.001	3	15
LARGE_INTESTINE	Positive regulation of proteolysis →	+0.081	+1.685	.001	<.001	3	9
STOMACH	Regulation of follicle-stimulating hormone secretion →	+0.998	+1.455	.001	.007	3	8
STOMACH	Positive regulation of follicle-stimulating hormone secretion →	+0.998	+1.455	.001	.007	3	8
PANCREAS	Negative regulation of follicle-stimulating hormone secretion →	+0.998	+1.449	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,078 associations by consensus.

Morula formation by TFAP2C expression — CNS

Explore this box plot interactively →