TFAP2B

Across TCGA patient cohorts, TFAP2B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,985 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TFAP2B-associated GO terms across cancer lineages are Establishment of tissue polarity, Obsolete histone H4-K16 acetylation, and Peptidyl-lysine methylation. Each is linked with TFAP2B in more than 13 cancer types. Because this analysis shows association rather than direction, both TFAP2B-to-partner and partner-to-TFAP2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of tissue polarity grouped by TFAP2B-low versus TFAP2B-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP2B→partner) and Y-score (partner→TFAP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Establishment of tissue polarity →	+0.058	+0.731	<.001	<.001	3	14
TGCT	Obsolete histone H4-K16 acetylation →	+0.063	+0.621	<.001	<.001	3	13
HNSC	Peptidyl-lysine methylation →	+0.025	+0.134	<.001	<.001	3	12
STAD	Negative regulation of Wnt signaling pathway →	+0.068	+0.109	<.001	<.001	2	13
TGCT	Mitochondrial membrane organization →	+0.037	+0.711	<.001	<.001	3	12
TGCT	Morphogenesis of a polarized epithelium →	+0.048	+0.749	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,985 associations by consensus.

Establishment of tissue polarity by TFAP2B expression — TGCT

Explore this box plot interactively →