TFAP2B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TFAP2B protein abundance is significantly associated with the RNA expression of many other genes, with 2,751 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TFAP2B-associated genes across cancer lineages are DGKH, SH3D19, and KLF9. Each is linked with TFAP2B in more than 1 cancer types. Because this analysis shows association rather than direction, both TFAP2B-to-partner and partner-to-TFAP2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFAP2B versus DGKH in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP2B→partner) and Y-score (partner→TFAP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADGKH →+0.554+0.643<.001<.00132
CCRCCSH3D19 →+0.650+0.656<.001.00132
CCRCCKLF9 →+1.201+0.750.003<.00132
BRCAGUCY1A2 →+0.678+0.844<.001<.00132
CCRCCTBRG1 →+0.455+0.716.006<.00132
BRCATMEM135 →+0.644+0.666<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,751 associations by consensus.

TFAP2B vs DGKH — BRCA

Per-sample scatter of TFAP2B vs DGKH in BRCA (Pearson r = 0.39).

Explore this scatter interactively →

Exploration