TEX9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TEX9 mutation is significantly associated with the RNA expression of many other genes, with 584 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX9-associated genes across cancer lineages are RNA5SP73, RNA5SP419, and RPS19P6. Each is linked with TEX9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX9-to-partner and partner-to-TEX9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP73 grouped by TEX9-low versus TEX9-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX9→partner) and Y-score (partner→TEX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNA5SP73 →+0.446+6.837<.001<.00132
UCECRNA5SP419 →+0.549+2.077<.001.00732
HNSCRPS19P6 →+0.104+5.368<.001.00532
HNSCRNU2-8P →+0.448+7.132<.001<.00131
BLCARN7SL25P →+0.330+4.396<.001.00231
BLCASNORD116-22 →+0.342+4.859<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 584 associations by consensus.

RNA5SP73 by TEX9 expression — CESC

Box plot of RNA5SP73 in TEX9-low vs TEX9-high samples in CESC.

Explore this box plot interactively →

Exploration