TEX9

Across TCGA cell cohorts, TEX9 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX9-associated genes across cancer lineages are OC90, ECE2, and CLEC4F. Each is linked with TEX9 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX9-to-partner and partner-to-TEX9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OC90 grouped by TEX9-low versus TEX9-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX9→partner) and Y-score (partner→TEX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	OC90 →	+0.006	+5.357	<.001	.003	3	1
LARGE_INTESTINE	ECE2 →	+0.330	+4.376	<.001	<.001	3	1
LARGE_INTESTINE	CLEC4F →	+0.246	+3.974	.001	.002	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.076	+4.108	.002	.008	3	1
LARGE_INTESTINE	WDR87 →	+0.025	+4.353	<.001	.001	3	1
LARGE_INTESTINE	KRT73 →	+0.070	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OC90 by TEX9 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →