TEX55

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TEX55 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TEX55 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TEX55 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TEX55 expression acts as an unfavorable survival marker.

BRCA and OV are the cancer types where TEX55 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSMedianII,III,IV0.3350.913.00530view →
OVDFSMedianAll0.0920.541<.00118view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TEX55–BRCA (OS)

Kaplan–Meier survival curve for TEX55 mutant vs wild-type samples in BRCA.

Open the BRCA breakdown →

Exploration