TEX53

Across TCGA cell cohorts, TEX53 RNA expression is significantly associated with the go_rna of many other GO terms, with 460 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TEX53-associated GO terms across cancer lineages are Negative regulation of ATP metabolic process, Positive regulation of NK T cell activation, and Intestine smooth muscle contraction. Each is linked with TEX53 in more than 3 cancer types. Because this analysis shows association rather than direction, both TEX53-to-partner and partner-to-TEX53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of ATP metabolic process grouped by TEX53-low versus TEX53-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX53→partner) and Y-score (partner→TEX53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of ATP metabolic process →	+0.095	+0.058	.005	.007	3	4
BLOOD_Myeloma	Positive regulation of NK T cell activation →	-0.159	-0.172	.002	.002	3	4
SKIN	Intestine smooth muscle contraction →	+0.749	+0.056	.002	<.001	3	3
BLOOD_Leukemia	Placenta blood vessel development →	+0.133	+0.055	.001	.002	3	3
CNS	Positive regulation of IRE1-mediated unfolded protein response →	+0.075	+0.047	.006	.001	3	3
STOMACH	Immunoglobulin transcytosis in epithelial cells →	-0.897	-0.037	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 460 associations by consensus.

Negative regulation of ATP metabolic process by TEX53 expression — SKIN

Explore this box plot interactively →