Across TCGA cell cohorts, TEX46 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,720 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TEX46-associated GO terms across cancer lineages are Regulation of cytoplasmic translational initiation, Negative regulation of DNA-templated transcription initiation, and Negative regulation of transcription initiation by RNA polymerase II. Each is linked with TEX46 in more than 5 cancer types. Because this analysis shows association rather than direction, both TEX46-to-partner and partner-to-TEX46 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX46→partner) and Y-score (partner→TEX46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of cytoplasmic translational initiation →	+0.067	+0.102	.008	.006	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated transcription initiation →	+0.098	+0.162	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription initiation by RNA polymerase II →	+0.098	+0.162	<.001	.003	3	5
LUNG_NSCLC_LUSC	DNA repair-dependent chromatin remodeling →	+0.081	+0.203	.009	.007	2	6
LARGE_INTESTINE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.150	+0.132	.001	.002	3	5
LARGE_INTESTINE	tRNA transcription by RNA polymerase III →	+0.052	+0.117	.006	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,720 associations by consensus.

Exploration

TEX46 survival (RNA) · tumor vs normal (RNA) · all TEX46 data types