TEX44

Across TCGA patient cohorts, TEX44 mutation is significantly associated with the RNA expression of many other genes, with 434 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX44-associated genes across cancer lineages are MIR6085, RNA5SP507, and RNU6-937P. Each is linked with TEX44 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX44-to-partner and partner-to-TEX44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6085 grouped by TEX44-low versus TEX44-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX44→partner) and Y-score (partner→TEX44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6085 →	+0.579	+2.484	<.001	.005	3	2
UCEC	RNA5SP507 →	+0.390	+2.677	<.001	.004	3	2
UCEC	RNU6-937P →	+0.428	+2.341	.008	.008	3	2
UCEC	HMGN2P16 →	+0.352	+2.656	<.001	.003	3	2
UCEC	LINC01022 →	+0.212	+3.336	<.001	<.001	3	2
UCEC	HTR3E-AS1 →	+0.323	+3.065	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 434 associations by consensus.

MIR6085 by TEX44 expression — UCEC

Explore this box plot interactively →