Across TCGA cell cohorts, TEX43 RNA expression is significantly associated with the mutation status of many other genes, with 301 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TEX43-associated genes across cancer lineages are NRROS, DSTYK, and ERBB4. Each is linked with TEX43 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEX43-to-partner and partner-to-TEX43 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX43→partner) and Y-score (partner→TEX43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NRROS →	+4.384	+0.084	.006	<.001	3	3
BLOOD_Leukemia	DSTYK →	+4.969	+0.105	.003	<.001	3	2
URINARY_TRACT	ERBB4 →	+4.087	+0.097	.009	<.001	3	2
BLOOD_Leukemia	EPHA6 →	+3.969	+0.070	.009	<.001	3	2
LUNG_SCLC	SETD1A →	+3.523	+0.194	.008	<.001	3	2
LUNG_SCLC	PHKB →	+4.523	+0.245	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 301 associations by consensus.

Exploration

TEX43 survival (RNA) · tumor vs normal (RNA) · all TEX43 data types