TEX36

Across TCGA patient cohorts, TEX36 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX36-associated genes across cancer lineages are ATM, GAPDH, and N-Ras. Each is linked with TEX36 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX36-to-partner and partner-to-TEX36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by TEX36-low versus TEX36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX36→partner) and Y-score (partner→TEX36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.525	-3.000	.045	.037	3	2
UCEC	GAPDH →	+0.724	+3.000	.019	.036	3	1
UCEC	N-Ras →	-0.158	-2.986	.021	.037	3	1
UCEC	SCD →	-0.146	-2.986	.021	.037	3	1
UCEC	Bax →	+0.357	+3.000	.010	.037	3	1
UCEC	Caspase-8 →	-0.305	-3.000	.035	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

ATM by TEX36 expression — UCEC

Explore this box plot interactively →