TEX36

Across TCGA cell cohorts, TEX36 mutation is significantly associated with the mutation status of many other genes, with 1,593 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX36-associated genes across cancer lineages are GABRP, CBX5, and NXPE1. Each is linked with TEX36 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX36-to-partner and partner-to-TEX36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GABRP grouped by TEX36-low versus TEX36-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX36→partner) and Y-score (partner→TEX36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GABRP →	+3.329	+3.799	.005	.005	1	1
LARGE_INTESTINE	CBX5 →	+3.329	+3.799	.005	.005	1	1
LARGE_INTESTINE	NXPE1 →	+3.744	+4.044	.003	.003	1	1
LARGE_INTESTINE	BTAF1 →	+2.574	+4.182	.003	.003	1	1
LARGE_INTESTINE	IKZF5 →	+3.329	+3.799	.005	.005	1	1
LARGE_INTESTINE	SORBS1 →	+2.043	+3.693	.009	.009	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,593 associations by consensus.

GABRP by TEX36 expression — LARGE_INTESTINE

Explore this box plot interactively →