TEX35

Across TCGA pan-cancer cohorts, TEX35 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of TEX35’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where TEX35 RNA is repressed in tumor relative to normal tissue. In most cancer types TEX35 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, LUSC, and BRCA are the cancer types where TEX35 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEX35 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.027	.001	5	view →
LUSC	Male	All	+0.119	<.001	4	view →
BRCA	Female	All	+0.040	<.001	4	view →
CHOL	All	All	+0.100	.013	2	view →
LUAD	All	All	+0.045	.036	1	view →
LIHC	All	All	+0.009	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

TEX35–KICH

Open the KICH breakdown →