Across TCGA patient cohorts, TEX33 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX33-associated genes across cancer lineages are Src_pY527, eEF2, and EGFR. Each is linked with TEX33 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX33-to-partner and partner-to-TEX33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX33→partner) and Y-score (partner→TEX33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Src_pY527 →	-0.444	-3.159	.012	.019	3	2
UCEC	eEF2 →	+0.348	+1.807	.018	.027	3	1
UCEC	EGFR →	-0.204	-3.459	.001	.005	3	1
UCEC	ERK2 →	+0.231	+2.115	.003	.017	3	1
UCEC	Gab2 →	+0.469	+3.321	.001	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.187	-2.115	.007	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

TEX33 survival (RNA) · tumor vs normal (RNA) · all TEX33 data types