Across TCGA cell cohorts, TEX33 mutation is significantly associated with the mutation status of many other genes, with 923 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX33-associated genes across cancer lineages are PDK4, P4HB, and HSPA14. Each is linked with TEX33 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX33-to-partner and partner-to-TEX33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX33→partner) and Y-score (partner→TEX33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PDK4 →	+3.350	+4.584	.003	.003	1	2
LARGE_INTESTINE	P4HB →	+3.350	+4.584	.003	.003	1	2
LARGE_INTESTINE	HSPA14 →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	GSTA1 →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	COCH →	+3.087	+4.392	.005	.005	1	2
LARGE_INTESTINE	KLF8 →	+3.672	+4.799	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 923 associations by consensus.

Exploration

TEX33 survival (RNA) · tumor vs normal (RNA) · all TEX33 data types