TEX30

Across TCGA pan-cancer cohorts, TEX30 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TEX30 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TEX30 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TEX30 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

HNSC, LSCC, and PDAC are the cancer types where TEX30 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.679	0.932	.005	15	view →
LSCC	DFS	Median	All	0.805	0.604	.017	8	view →
PDAC	DFS	Median	All	0.758	0.870	.036	6	view →
GBM	OS	Quartile	All	0.669	0.254	.005	5	view →
LUAD	OS	Median	III,IV	1.000	0.262	.013	3	view →
CCRCC	OS	Median	II,III,IV	0.610	0.888	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TEX30–HNSC (DFS)

Open the HNSC breakdown →