TEX30

Across TCGA patient cohorts, TEX30 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX30-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, EGFR_pY1068, and ERK2. Each is linked with TEX30 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX30-to-partner and partner-to-TEX30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by TEX30-low versus TEX30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX30→partner) and Y-score (partner→TEX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.655	+2.906	.002	.001	3	2
UCEC	EGFR_pY1068 →	-0.279	-1.700	.008	.044	3	1
UCEC	ERK2 →	+0.200	+2.222	.014	.011	3	1
UCEC	GSK3-a-b →	-0.153	-1.700	.007	.044	3	1
UCEC	JNK_pT183_Y185 →	-0.169	-2.321	.018	.034	3	1
UCEC	Lck →	+0.200	+3.000	.018	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Acetyl-a-Tubulin-Lys40 by TEX30 expression — UCEC

Explore this box plot interactively →