TEX30

Across TCGA cell cohorts, TEX30 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX30-associated genes across cancer lineages are LHCGR, ELOA3DP, and FGF3. Each is linked with TEX30 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX30-to-partner and partner-to-TEX30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LHCGR grouped by TEX30-low versus TEX30-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX30→partner) and Y-score (partner→TEX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LHCGR →	+0.050	+4.467	<.001	.004	3	1
LARGE_INTESTINE	ELOA3DP →	+0.031	+4.273	<.001	.006	3	1
CNS	FGF3 →	+0.043	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LHCGR by TEX30 expression — LARGE_INTESTINE

Explore this box plot interactively →