TEX264

Across TCGA pan-cancer cohorts, TEX264 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TEX264 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TEX264 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TEX264 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, CCRCC, and GBM are the cancer types where TEX264 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.836	0.515	<.001	39	view →
CCRCC	DFS	Median	II,III,IV	0.451	0.777	.005	11	view →
GBM	DFS	Quartile	All	0.188	0.390	.007	11	view →
LSCC	DFS	Tertile	III,IV	0.376	0.798	.045	6	view →
LUAD	DFS	Quartile	III,IV	0.846	0.282	.039	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TEX264–HNSC (DFS)

Open the HNSC breakdown →