Across TCGA pan-cancer cohorts, TEX26-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TEX26-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher TEX26-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TEX26-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and SKCM show a favorable association.

MESO, CESC, and LGG are the cancer types where TEX26-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.501	0.284	.001	50	view →
CESC	OS	Tertile	III,IV	0.206	0.681	.003	50	view →
LGG	OS	Median	All	0.737	0.875	<.001	49	view →
LUSC	OS	Median	All	0.288	0.478	.001	33	view →
KIRC	DFS	Median	All	0.510	0.700	<.001	30	view →
UVM	DFS	Tertile	II,III,IV	0.374	0.625	.012	27	view →
KIRP	DFS	Quartile	All	0.785	0.933	.002	25	view →
SKCM	OS	Median	All	0.393	0.276	.002	24	view →
STAD	OS	Tertile	All	0.374	0.617	.004	20	view →
GBM	DFS	Quartile	All	0.184	0.340	.008	18	view →
UCS	DFS	Tertile	II,III,IV	0.567	0.159	.007	18	view →
PAAD	DFS	Median	All	0.417	0.533	.023	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration

Same gene, other analysis: TEX26-AS1 tumor-vs-normal RNA expression · all TEX26-AS1 data types