TEX2

Across TCGA cell cohorts, TEX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,405 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TEX2-associated GO terms across cancer lineages are Negative regulation of beige fat cell differentiation, Mitochondrion localization, and DNA-templated transcription initiation. Each is linked with TEX2 in more than 10 cancer types. Because this analysis shows association rather than direction, both TEX2-to-partner and partner-to-TEX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of beige fat cell differentiation grouped by TEX2-low versus TEX2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX2→partner) and Y-score (partner→TEX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of beige fat cell differentiation →	+0.178	+0.833	.001	.001	3	11
OESOPHAGUS	Mitochondrion localization →	+0.084	+0.666	<.001	.008	3	10
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.072	+0.889	.002	.002	3	10
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.106	+1.334	<.001	<.001	3	9
LARGE_INTESTINE	Response to nerve growth factor →	+0.082	+0.581	<.001	<.001	3	9
STOMACH	Very long-chain fatty acid catabolic process →	+0.134	+0.643	<.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,405 associations by consensus.

Negative regulation of beige fat cell differentiation by TEX2 expression — LIVER

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