TEX14

Across TCGA cell cohorts, TEX14 mutation is significantly associated with the RNA expression of many other genes, with 1,422 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX14-associated genes across cancer lineages are SPATA19, DUSP29, and C10orf62. Each is linked with TEX14 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX14-to-partner and partner-to-TEX14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA19 grouped by TEX14-low versus TEX14-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX14→partner) and Y-score (partner→TEX14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SPATA19 →	+0.056	+3.256	<.001	.005	3	2
LUNG_SCLC	DUSP29 →	+0.058	+3.232	<.001	.008	3	2
LUNG_SCLC	C10orf62 →	+0.069	+3.991	<.001	.001	3	2
LARGE_INTESTINE	ACBD5 →	+0.905	+2.949	<.001	<.001	3	2
LARGE_INTESTINE	TVP23B →	+0.629	+2.265	<.001	.001	3	2
LARGE_INTESTINE	ZFAND4 →	+0.908	+2.949	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,422 associations by consensus.

SPATA19 by TEX14 expression — LUNG_SCLC

Explore this box plot interactively →