TEX13C

Across TCGA cell cohorts, TEX13C RNA expression is significantly associated with the go_rna of many other GO terms, with 377 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TEX13C-associated GO terms across cancer lineages are SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of interleukin-6 production. Each is linked with TEX13C in more than 4 cancer types. Because this analysis shows association rather than direction, both TEX13C-to-partner and partner-to-TEX13C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition grouped by TEX13C-low versus TEX13C-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX13C→partner) and Y-score (partner→TEX13C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.077	+0.400	.007	.008	3	5
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.084	+0.495	<.001	.003	3	4
SKIN	Regulation of interleukin-6 production →	-0.042	-0.368	.001	.007	3	3
SKIN	Negative regulation of gene expression, epigenetic →	+0.030	+0.452	<.001	.006	2	4
SKIN	Potassium ion transmembrane transport →	-0.050	-0.502	<.001	.008	3	3
SKIN	Positive regulation of protein folding →	+0.119	+0.480	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 377 associations by consensus.

SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition by TEX13C expression — SKIN

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