TEX13A

Across TCGA patient cohorts, TEX13A mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX13A-associated genes across cancer lineages are Notch1, TFRC, and Ku80. Each is linked with TEX13A in more than 2 cancer types. Because this analysis shows association rather than direction, both TEX13A-to-partner and partner-to-TEX13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by TEX13A-low versus TEX13A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX13A→partner) and Y-score (partner→TEX13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.147	+2.125	.004	.010	3	3
SKCM	TFRC →	+0.749	+3.169	.003	.017	3	2
UCEC	Ku80 →	+0.238	+1.688	.006	.013	3	2
UCEC	STAT5a →	+0.322	+2.222	.028	.010	3	2
UCEC	ASNS →	+0.473	+3.000	<.001	<.001	3	2
UCEC	Caspase-8 →	-0.257	-3.973	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Notch1 by TEX13A expression — UCEC

Explore this box plot interactively →