TEX13A

Across TCGA cell cohorts, TEX13A mutation is significantly associated with the mutation status of many other genes, with 1,139 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX13A-associated genes across cancer lineages are MYH2, PCDHA2, and RBM20. Each is linked with TEX13A in more than 2 cancer types. Because this analysis shows association rather than direction, both TEX13A-to-partner and partner-to-TEX13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH2 grouped by TEX13A-low versus TEX13A-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX13A→partner) and Y-score (partner→TEX13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	MYH2 →	+4.392	+4.954	.008	.008	1	3
LUNG_NSCLC_LUAD	PCDHA2 →	+2.893	+3.321	.003	.003	1	3
LARGE_INTESTINE	RBM20 →	+2.289	+3.182	.008	.008	1	3
LARGE_INTESTINE	MYH8 →	+1.874	+3.700	.005	.005	1	3
SKIN	SLC22A23 →	+4.357	+4.053	.001	.001	1	2
SKIN	BBS7 →	+3.772	+3.772	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,139 associations by consensus.

MYH2 by TEX13A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →