TEX101

Across TCGA pan-cancer cohorts, TEX101 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TEX101 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TEX101 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TEX101 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

ACC, HNSC, and LIHC are the cancer types where TEX101 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.010	0.667	<.001	45	view →
HNSC	OS	Median	All	0.198	0.768	.001	33	view →
LIHC	OS	Median	All	0.204	0.777	.008	15	view →
SKCM	DFS	Median	IV	1.000	0.201	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TEX101–ACC (DFS)

Open the ACC breakdown →