TEX101

Across TCGA cell cohorts, TEX101 RNA expression is significantly associated with the go_rna of many other GO terms, with 642 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TEX101-associated GO terms across cancer lineages are Positive regulation of complement activation, Negative regulation of response to endoplasmic reticulum stress, and Cell-substrate junction organization. Each is linked with TEX101 in more than 4 cancer types. Because this analysis shows association rather than direction, both TEX101-to-partner and partner-to-TEX101 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of complement activation grouped by TEX101-low versus TEX101-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX101→partner) and Y-score (partner→TEX101) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of complement activation →	+1.073	+0.039	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of response to endoplasmic reticulum stress →	+0.080	+0.105	<.001	.003	3	4
SKIN	Cell-substrate junction organization →	+0.090	+0.023	<.001	.002	3	4
SKIN	Regulation of heart rate by chemical signal →	+0.111	+0.021	.008	.006	3	4
SKIN	Wound healing →	+0.049	+0.041	.002	.002	3	4
SKIN	Cell-substrate junction assembly →	+0.104	+0.023	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 642 associations by consensus.

Positive regulation of complement activation by TEX101 expression — SKIN

Explore this box plot interactively →