Across TCGA patient cohorts, TET3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,467 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TET3-associated proteins across cancer lineages are ADNP, RALY, and SF3B3. Each is linked with TET3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TET3-to-partner and partner-to-TET3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TET3→partner) and Y-score (partner→TET3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADNP →	+0.363	+0.618	<.001	<.001	3	7
PDAC	RALY →	+0.247	+0.250	.004	.004	3	6
LSCC	SF3B3 →	+0.210	+0.756	<.001	<.001	3	6
LSCC	SSB →	+0.382	+0.789	<.001	<.001	3	6
LSCC	ACTL6A →	+0.327	+0.716	<.001	<.001	3	6
LSCC	WRNIP1 →	+0.328	+0.517	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,467 associations by consensus.

Exploration

TET3 survival (RNA) · tumor vs normal (RNA) · all TET3 data types