TESK1

Across TCGA patient cohorts, TESK1 RNA expression is significantly associated with the mutation status of many other genes, with 7,767 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TESK1-associated genes across cancer lineages are TP53, MUC16, and FAM135B. Each is linked with TESK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TESK1-to-partner and partner-to-TESK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by TESK1-low versus TESK1-high in GBM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TESK1→partner) and Y-score (partner→TESK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TP53 →	+2.038	+0.453	<.001	<.001	3	5
UCEC	MUC16 →	+0.963	+0.187	<.001	.004	3	4
UCEC	FAM135B →	+1.476	+0.293	<.001	<.001	3	4
UCEC	KIF26B →	+2.036	+0.385	<.001	<.001	3	4
LUSC	FSHR →	+4.483	+0.467	<.001	<.001	3	3
CESC	HECTD4 →	+3.244	+0.399	.008	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,767 associations by consensus.

TP53 by TESK1 expression — GBM

Explore this box plot interactively →